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Thus, the GLP-1RA keeps plasma glucose concentrations at lower levels without increasing the risk of hypoglycaemia.63 Additional effects include decreased gastric emptying, increased satiety, and decreased appetite and food intake leading to body weight loss63 with reduction of fat mass, android fat, trunk fat and lean body mass.64 65.
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Objective: To study the plasma lipidome of patients with anorexia nervosa (AN) before and after weight restoration treatment and report associations with AN subtypes and oral contraceptive pill (OCP) usage. Methods: Quantitative shotgun lipidomics analysis was used to study plasma lipids of 50 female patients with AN before and after weight restoration treatment and 50 healthy female controls.
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Body mass index (Age 13) and fear of weight gain (Age 14) were consistent predictors of maladaptive exercise across sex. Results support re-framing motivations for exercise in youth away from weight loss at a population level and targeting reductions in fear of weight gain for high-risk individuals. ALSPAC; Maladaptive exercise; adolescence.
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